Sunday, July 24, 2005

Green Tea Supplement

Green tea has been used traditionally in China for thousands of years for its health-preserving and revitalizing power. Modern science has identified powerful antioxidants in green tea called polyphenols. One group of polyphenols called catechins is particularly potent and highly effective at neutralizing free radicals at the cellular level. Catechins support healthy cell function while providing antioxidant protection to critical cell structures such as DNA. Demonstrated to cause a thermogenic effect, catechins also enhance the body's metabolic rate.*


Tegreen 97® from Pharmanex® is a proprietary, highly concentrated extract of the catechins found in green tea. As one of the most potent antioxidant supplements on the market, Tegreen 97® has a 97% polyphenol content, 65% of which are catechins. Each Tegreen 97® capsule contains the catechin equivalent of approximately seven cups of green tea and is 99.5% caffeine free. Recent clinical studies show consuming 400 to 600 mg of catechins at one time will more effectively increase the level of catechins in the blood and increase the amount of time they stay in the body.*


The following abstract is one of many from multiple, ongoing scientific case studies on antioxidants and their relationship to our health. If you are unfamiliar with scientific studies, they are typically summarized in abstract form. Your medical doctor can further assist you in understanding any medical terminology or references contained within the following abstract.


GREEN TEA

Effect of increased tea consumption on oxidative DNA damage among smokers: a randomized controlled study.

ABSTRACT: Tea drinking has been associated with decreased occurrence of cancer and heart disease. One potential mechanism for these findings is the strong antioxidant effect of tea polyphenols. A phase II randomized controlled tea intervention trial was designed to study the effect of high consumption (4 cups/d) of decaffeinated green or black tea on oxidative DNA damage as measured by urinary 8-hydroxydeoxyguanosine (8-OHdG) among smokers over a 4-mo period. A total of 143 heavy smokers, aged 18-79 y, were randomized to drink either green or black tea or water. Levels of plasma and urinary catechins and urinary 8-OHdG were measured monthly. A total of 133 of 143 smokers completed the 4-mo intervention. Multiple linear regression models were used to estimate the main effects and interaction effect of green and black tea consumption on creatinine-adjusted urinary 8-OHdG, with or without adjustment for potential confounders. Plasma and urinary levels of catechins rose significantly in the green tea group compared with the other two groups. Assessment of urinary 8-OHdG after adjustment for baseline measurements and other potential confounders revealed a highly significant decrease in urinary 8-OHdG (-31%) after 4 mo of drinking decaffeinated green tea (P = 0.002). No change in urinary 8-OHdG was seen among smokers assigned to the black tea group. This data suggests that regular green tea drinking might protect smokers from oxidative damages and could reduce cancer risk or other diseases caused by free radicals associated with smoking. Mel and Enid Zuckerman Arizona College of Public Health, University of Arizona, Tucson, AZ 85724, USA. ihakim@azcc.arizona.edu

AUTHOR(S): Hakim IA, Harris RB, Brown S, Chow HH, Wiseman S, Agarwal S, Talbot W.

JOURNAL: J Nutr. 2003 Oct; 133(10):3303S-3309S.


*This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.


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Saturday, July 16, 2005

Tried and True

It just doesn't get any better than the Harvard School of Public Health, when looking for objective sources of information on nutrition and a healthier lifestyle. It is such a great resource for finding answers to many tough questions about nutrition and health, that I have added it to my links at the right side bar of my blog.

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Your Feedback

Providing resources and information to you can be time consuming to say the least. Researching resources taking up the bulk of that time. However, it is a passion of mine to help educate people so that they can make informed decisions for what works best for them. Admittedly, my blog is relatively new, but is beginning to gain momentum as shown by my statcounter displayed at right side bottom of my blog. I am also starting to see return visits which tells me that there are people truly interested in living better, longer.

For those who are new to my blog, let me tell you that for me to post something here, is predicated primarily on the fact of whether or not something has scientific basis. Scientific proof is key and measurement is the basis of all science.

Considering the time aspect of maintaining my blog, if there is any particular subject or topic that any of you would like me to research or provide information on, please let me know. I have several return visitors that I would love to hear from. Feedback or input from all is most welcome and would be most appreciated. The goal is to educate, provide resources, products and information to the most people as efficiently as possible.


"To believe in yourself is to believe that you can achieve optimal health and wealth."


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Saturday, July 09, 2005

Selecting a Good Vitamin & Mineral Supplement Part IV


The measurable Difference!


The Products

LifePak®


In order for each of us to reach our peak level of health, and then maintain it throughout our lives, we need to start with a firm foundation of basic nutrition. Science has discovered that this foundation is comprised of antioxidants, micronutrients, and macronutrients - compounds essential to optimal health.

Even if we manage to eat a well-balanced diet, getting all the micronutrients we need is difficult. That's why Pharmanex has created a comprehensive micronutrient supplement that provides optimal levels of important vitamins and minerals, as well as a comprehensive arsenal of antioxidants, making LifePak® superior to any other supplement available.


MarineOmega™ and LifePak®


Unlike micronutrients, which are commonly deficient from out diets, most of us suffer from excesses in macronutrients, including proteins, carbohydrates, and fats. However, there are important macronutrients that are commonly deficient in most diets - omega-3 fatty acids. Because these are essential to optimal health, Pharmanex includes MarineOmega™ in our foundation for optimal nutrition.

Used together, LifePak® and MarineOmega™ constitute the most comprehensive anti-aging supplement program available. The combination of the two products provides your body with optimal levels of essential micronutrients and macronutrients typically lacking in most diets and are necessary for longevity and wellness. MarineOmega™ also works with LifePak® by enhancing nutrient bioavailability for maximum health.


Pharmanex® BioPhotonic Scanner


The Free Radical Problem

Our bodies are under attack. Each day we are exposed to free radicals - unstable molecules that steal or "scavenge" electrons from other molecules. Many of the physical effects we call "aging" are the result of free radicals, which damage tissue such as skin, blood vessels, and the brain.


Nature's Solution - Antioxidants

Antioxidants are your first defense against free radical attacks - they freely share their electrons and stop the degenerative chain reaction of free radicals. Our bodies naturally generate some antioxidants, and certain foods also contain antioxidants.

However, new research shows these sources may not provide sufficient antioxidant protection against a growing onslaught of free radical invaders.


How do you know if you have a healthy level of anitoxidants?

You Measure Your Results.


The Pharmanex® BioPhotonic Scanner is the world's first measuring tool that gives you a Skin Carotenoid Score (SCS) - immediate evidence of carotenoid antioxidant activity in your body. By simply placing your hand in front of a low-energy blue light laser, you get your score and become empowered to make improvements to your antioxidant health through nutritious eating and supplementation with LifePak®.


The technology of the Pharmanex® BioPhotonic Scanner is based on an optical method known as Resonance Raman Spectroscopy. This technology has been used for many years in research laboratories and more recently for carotenoid investigations in biological systems.

The scanner measures carotenoid levels in human tissue at the skin surface using optical signals. These signals identify the unique molecular structure of carotenoids, allowing their measurement without interference by other molecular substances and providing the person being measured with an SCS. Pharmanex is the exclusive owner of the patented biophotonic scanner technology for measurement of skin carotenoids in a non-medical environment.


For a more comprehensive look at LifePak®


For a more comprehensive look at MarineOmega™


To view the Pharmanex® Biophotonic Scanner video, click on a link below.


high speed Windows Media Player OR high speed Quicktime Media Player


dial-up Windows Media Player OR dial-up Quicktime Media Player


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You Decide!


Click Photo to enlarge for DETAILS!

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Sunday, July 03, 2005

Selecting a Good Vitamin & Mineral Supplement Part III


The Process

The 6S Quality Guarantee


Pharmanex® uses proprietary technology in its manufacturing process to maintain tight quality controls through all stages of product development. The key to consistent quality is the Pharmanex 6S Quality Process, the basis of the company's pharmaceutical approach to product development. By applying this process, Pharmanex has consistently met or exceeded the Good Manufacturing Practices (GMP) standards set by the FDA for this product category. The 6S Quality Process has enabled Pharmanex to become an industry leader in quality and efficacy.

Selection
To locate the botanicals with the most effective health-promoting properties, Pharmanex employs teams of experts from the United States and Asia. These teams conduct exhaustive research-compiling, reviewing, and summarizing historical use and current intelligence about a botanical's properties and health benefits. Pharmanex also conducts original research to identify new botanicals, coordinating with noted professionals at Purdue University, Kansas University, Columbia University, Scripps Research Institute, and Beijing University, among others. Only botanicals that pass extensive Pharmanex tests for authenticity, usefulness, and safety are considered.

Sourcing
Once Pharmanex decides to proceed with a particular botanical, a team investigates potential sources of the botanical and conducts exhaustive analyses on samples from each source. Sources may be domestic or international and may include Pharmanex cultivation areas in China and Chile. Pharmanex chooses a supplier based on the quality and concentration level of the active ingredient(s) present in samples from that source.

Structure
Using state-of-the-art analytical techniques and working in collaboration with respected universities and laboratories in both China and the United States, Pharmanex conducts structural analyses of the natural compounds present in the selected botanical. These analyses isolate and purify specific chemical structures in standardized extracts, a critical step in ensuring a safe and effective botanical.

Standardization
Wide variations in active ingredients are characteristic of any botanical. For example, when Pharmanex analyzes potential Ginkgo biloba leaves, studies reveal the concentrations of active components will vary by as much as 300% depending on season, climate, soil, method of harvest, storage conditions, and processing. Pharmanex optimizes the active ingredients of a product through strict, proprietary standardization processes (to at least one relevant marker molecule). Each capsule of a Pharmanex product contains the same amount of each active ingredient.

Safety
Pharmanex is leading the way in establishing strict standards to ensure the safety of its products. Scientists research and document the history of a product's use and safety. Pharmaceutical-grade tests for the presence of microbes, toxins, and heavy metals are carried out for all products. The active ingredient amount used is based on dosages found effective through clinical trials and is backed by published data on file at Pharmanex. Each product label details directions for use and contains appropriate warning information.

Substantiation
Pharmanex only makes product claims that have been substantiated through documented preclinical and clinical studies. Existing clinical data are reviewed, and when necessary, Pharmanex sponsors studies of its products. Data from some of these studies are subsequently submitted to major international journals for review. This adherence to scientific standards for substantiation helps make Pharmanex a leader in the natural healthcare product industry.


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Friday, July 01, 2005

Selecting a Good Vitamin & Mineral Supplement Part II


The Company


The Pharmanex scientific team comprises medical researchers, clinicians, pharmacologists, botanists, medicinal chemists, pharmacognosists, nutritionists, process chemists, analytical chemists, biochemists, molecular biologists, immunologists, statisticians, toxicologists, exercise physiologists, quality control specialists, and clinical research specialists. More than 75 full-time scientists from three internal research centers confer together daily. This team has obtained dozens of patents and published scores of scientific papers that are internationally recognized. Past and present collaborations also include numerous universities and leading research centers across the world.

Pharmanex has also gathered together some of the greatest minds in the scientific world to form a renowned Scientific Advisory Board. The combination of internal scientists, research centers, and the Scientific Advisory Board comprises the most extraordinary group of scientists ever assembled by a nutritional company.

This diverse network promotes penetrating and clear-sighted discovery throughout every stage of the development process. Exploring new posibilities, testing hypotheses, contributing a diverse and abundant variety of expert viewpoints - all this illuminates and enriches the work, translating into the finest nutritional products in the industry.


"Pharmanex began 11 years ago with the vision that we could use the latest pharmaceutical science to bring out the best in natural products. We believed we could create superior dietary supplements of proven safety and efficacy that would benefit the world over. Today, we have achieved that vision.

Pharmanex is and always will be a company built on science. It is our passion and our calling. More importantly, it is our belief that without science, products of true value cannot be developed. Pharmanex has assembled an unprecedented worldwide association of renowned scientists and nutritionists. In addition, the distinguished Pharmanex Scientific Advisory Board participates actively in clinical research and product development and constitutes a product development engine unparalleled in the marketplace. We do not create unique products by reading tea leaves. Instead, we measure. We use real science. At its core, Pharmanex is a yardstick for the industry. Pharmanex is the Measurable Difference.

Pharmanex's dedication to science has also led to a revolution in the way we measure antioxidant status in our bodies. The Pharmanex BioPhotonic Scanner is the first tool that uses laser technology to non-invasively measure carotenoid antioxidant levels in the skin. With this technology, Pharmanex consumers can verify the benefits of daily supplementation.

I am passionate about who we are and what we do at Pharmanex. We truly are in a pivotal and exciting time in Pharmanex history. Our passion is everything nutritional that helps you to live better, longer. We invite you to be our ambassadors of health. Be part of the Measurable Difference."


Joseph Chang, Ph.D.

President

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